Genetics Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

Abbas Dehghan, MD, PhD*; Josée Dupuis, PhD*; Maja Barbalic, PhD*; Joshua C. Bis, PhD*; Gudny Eiriksdottir, MSc;* Chen Lu, MA; Niina Pellikka, BEng; Henri Wallaschofski, MD; Johannes Kettunen, MSci; Peter Henneman, MSc; Jens Baumert, PhD; David P. Strachan, MD; Christian Fuchsberger, PhD; Veronique Vitart, PhD; James F. Wilson, BSc, DPhil; Guillaume Paré, MD, MSc; Silvia Naitza, PhD; Megan E. Rudock, PhD; Ida Surakka, BSci; Eco J.C. de Geus, PhD; Behrooz Z. Alizadeh, PhD; Jack Guralnik, MD, PhD; Alan Shuldiner, MD; Toshiko Tanaka, PhD; Robert Y.L. Zee, PhD; Renate B. Schnabel, MD, MSc; Vijay Nambi, MD; Maryam Kavousi, MD, MSc; Samuli Ripatti, PhD; Matthias Nauck, MD; Nicholas L. Smith, PhD; Albert V. Smith, PhD; Jouko Sundvall, PhD; Paul Scheet, PhD; Yongmei Liu, MD, PhD; Aimo Ruokonen, MD, PhD; Lynda M. Rose, MSc; Martin G. Larson, ScD; Ron C. Hoogeveen, PhD; Nelson B. Freimer, MD; Alexander Teumer, Dipl-Math; Russell P. Tracy, PhD; Lenore J. Launer, PhD; Julie E. Buring, DSc; Jennifer F. Yamamoto, MA; Aaron R. Folsom, MD, MPH; Eric J.G. Sijbrands, MD, PhD; James Pankow, PhD; Paul Elliott, MBBS, PhD, FMedSci; John F. Keaney, MD; Wei Sun, MD, PhD; Antti-Pekka Sarin, BSci; João D. Fontes, MD; Sunita Badola, MSc; Brad C. Astor, PhD, MPH; Albert Hofman, MD, PhD; Anneli Pouta, MD, PhD; Karl Werdan, MD; Karin H. Greiser, MD; Oliver Kuss, PhD; Henriette E. Meyer zu Schwabedissen, MD; Joachim Thiery, MD; Yalda Jamshidi, PhD; Ilja M. Nolte, PhD; Nicole Soranzo, PhD; Timothy D. Spector, MD, MSc, FRCP; Henry Völzke, MD; Alexander N. Parker, PhD; Thor Aspelund, PhD; David Bates, MD, MSc; Lauren Young; Kim Tsui; David S. Siscovick, MD, MPH; Xiuqing Guo, PhD; Jerome I. Rotter, MD; Manuela Uda, PhD; David Schlessinger, PhD; Igor Rudan, MD; Andrew A. Hicks, PhD; Brenda W. Penninx, PhD; Barbara Thorand, PhD, MPH; Christian Gieger, PhD, MS; Joe Coresh, MD, PhD; Gonneke Willemsen, PhD; Tamara B. Harris, MD, MSc; Andre G. Uitterlinden, PhD; Marjo-Riitta Järvelin, MD, MSc, PhD; Kenneth Rice, PhD; Dörte Radke; Veikko Salomaa, MD, PhD; Ko Willems van Dijk, PhD; Eric Boerwinkle, PhD; Ramachandran S. Vasan, MD; Luigi Ferrucci, MD, PhD; Quince D. Gibson, MBA; Stefania Bandinelli, MD; Harold Snieder, PhD; Dorret I. Boomsma, PhD; Xiangjun Xiao; Harry Campbell, MBChB, MD; Caroline Hayward, PhD; Peter P. Pramstaller, MD; Cornelia M. van Duijn, PhD; Leena Peltonen, MD, PhD†; Bruce M. Psaty, MD, PhD; Vilmundur Gudnason, MD, PhD; Paul M. Ridker, MD, MPH; Georg Homuth, PhD*; Wolfgang Koenig, MD, PhD*; Christie M. Ballantyne, MD*; Jacqueline C.M. Witteman, PhD*; Emelia J. Benjamin, MD, ScM*; Markus Perola, MD, PhD*; Daniel I. Chasman, PhD*